Merck Sharp & Dohme Limited (MSD) welcomes the publication of the guideline for type 2 diabetes newer agents1 from the National Institute for Health and Clinical Excellence (NICE) in the UK, which recommends considering a range of newer therapy options, including Januvia (sitagliptin). The guideline recommends that the DPP4 inhibitor class, which includes sitagliptin, [...]

Variations in both milk feeding and in the weaning diet are linked to differences in growth and development, and they have independent influences on body composition in early childhood, according to a new study accepted for publication in The Endocrine Societys Journal of Clinical Endocrinology & Metabolism (JCEM).
Previous studies suggest that the early environment may [...]

President Obama on Tuesday in his official announcement of his nomination of Judge Sonia Sotomayor of the Second Circuit Court of Appeals to the Supreme Court emphasized what he called her “extraordinary journey” from a modest background to the top of the judiciary, launching a “confirmation battle that he hopes to wage over biography more [...]

Health officials recently held a regional consultation in Kenya to examine mothertochild HIV transmission services and pediatric HIV/AIDS care in nine Eastern and Southern African countries, IRIN/PlusNews reports. The consultation hosted by UNICEF, UNAIDS and the World Health Organization included representatives from Ethiopia, Kenya, Malawi, Mozambique, South Africa, Swaziland, Tanzania, Uganda and [...]

UroToday.com Angiogenesis is the process of new blood vessel formation in tumors, facilitating their growth. Endostatin is a cleavage product of collagen and is a potent inhibitor of endothelial cell proliferation and migration. Endostatin causes apoptosis in endothelial and tumor cells. Prostate cancer expresses angiogenic factors.
A missense mutation in the [...]

In selecting a Supreme Court nominee, President Obama will have a more diverse pool of judges to choose from than his predecessors did, largely because the number of women on the federal bench has increased dramatically over the past two decades, the AP/Kansas City Star reports. Just two of the 110 justices that have served [...]

A metaanalysis of five trials has shown that more intensive glucose control in type 2 diabetes leads to fewer heart attacks and heart disease events but has no significant effect on stroke or mortality from all causes. The findings are reported in an Article in this weeks diabetes special issue of The Lancet, written [...]

Newly released Census Bureau data show that even before the current economic recession began in September 2008, population growth among children younger than age one began to decline, the AP/Kansas City Star reports. Between July 2007 and July 2008, the number of children younger than age one in the U.S. increased 0.9%, compared with a [...]

Researchers from Weill Cornell Medical College have published results showing that a new contraceptive device may also effectively block the transmission of the HIV virus. Findings show that the device prevents infection by the HIV virus in laboratory testing. The promising results are published in the most recent issue of the journal AIDS.
The new device [...]

OGX011 survival benefit an even better Hazard Ratio.
With the release of ASCO abstracts last night we saw additional data and statistical analyses from OGXIs Phase II trial. This was a randomized, controlled Phase II trial in prostate cancer with their lead compound OGX011, that had shown a 10.6 month survival advantage, including a [...]