University of Michigan Health System researchers will lead a $10.25 million effort to study rare kidney diseases that cause kidney failure and the need for dialysis.
The fiveyear project supports research of nephrotic syndrome, which describes a group of diseases that, though rare, generates an enormous individual and societal burden. The syndrome, which affects kidney filter [...]

For kidney transplant recipients, infection with a virus called cytomegalovirus (CMV) may lead to devastating complications. New research suggests that extending the period of preventive treatment after kidney transplantation can reduce the risk of CMV disease, according to an upcoming report in the Journal of the American Society of Nephrology (JASN).
Cytomegalovirus is a common virus [...]

The National Cancer Institute (NCI) has awarded Beth Israel Deaconess Medical Center (BIDMC) an $11.5 million, fiveyear SPORE grant to focus on cancers of the kidney. Michael Atkins, MD, Deputy Director of BIDMCs Division of Hematology/Oncology, will oversee the grant, which involves collaborations with Brigham and Womens Hospital, DanaFarber Cancer Institute, and Massachusetts General Hospital [...]

Urovalve announced the successful results of a feasibility study of the Valve component of its Surinate® Bladder Management System designed to improve the quality of life of men who suffer from acute or chronic urinary retention, which is an inability to empty the bladder caused by obstruction of the urethra.
The [...]

The introduction of prostateantigen screening, or PSA, has resulted in over 1 million additional men over the last 23 years being diagnosed and treated for prostate cancer most of whom were likely overdiagnosed, researchers reported in a new study published online August 31 in the Journal of the National Cancer Institute.
Overdiagnosis has been associated [...]

A marker of the likely course of diabetic nephropathy (DN) has been found. An 18year study, published in the open access journal BMC Medicine, has shown that Immunoglobulin M (IgM) is a reliable predictor of cardiovascular complications in DN patients.
Omran Bakoush, MD, PhD, led a team of researchers from Lund University, Sweden, who carried out [...]

Researchers from Boston University School of Medicine (BUSM) in collaboration with scientists at the University of Louisville and the University of Nice Sophia Antipolis in France, have identified the target antigen PLA2R in patients with idiopathic membranous nephropathy (kidney disease), which has implications for the diagnosis and treatment of this disease. These findings appear in [...]

UroToday.com Two papers in the May 5, 2009 edition of Nature Genetics link ERG chromosomal gene translocations with loss of PTEN in the early stages of prostate cancer (CaP) progression. Both are reviewed in Urotoday.
In this report, Dr. Brett Carver and colleagues studied TMPRSS2ERG genetic rearrangement, which are reported in up to [...]

UroToday.com Together with Drs. Heruti, Bechor, Justo and Galor, we studied 815 Israeli male adults of whom 305 had complete data and were included in the statistical analysis. In the analyzed population, 2.1% of people without erectile dysfunction (ED) had advanced periodontal disease (defined as recession of periodontal bone of 6 mm or more) [...]

A team led by scientists at The Institute of Cancer Research (ICR) compared the genes of 730 men who had developed testicular cancer with the genes of healthy men. They found many of the men who had suffered cancer shared common DNA variants on chromosomes 5, 6 and 12 that the healthy men did not [...]